S-Nitrosylation: an emerging redox-based post-translational modification in plants
نویسندگان
چکیده
منابع مشابه
S-nitrosylation: an emerging redox-based post-translational modification in plants.
S-nitrosylation, the covalent attachment of a nitric oxide moiety to a cysteine thiol, is now established as a key post-translational modification in animals. This process has been shown to regulate the function of a wide variety of regulatory, structural, and metabolic proteins. The emerging evidence now suggests that S-nitrosylation may also have a central function in plant biology.
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BACKGROUND S100A1 protein is a proposed target of molecule-guided therapy for heart failure. RESULTS S-Nitrosylation of S100A1 is present in cells, increases Ca(2+) binding, and tunes the overall protein conformation. CONCLUSION Thiol-aromatic molecular switch is responsible for NO-related modification of S100A1 properties. SIGNIFICANCE Post-translational S-nitrosylation may provide funct...
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ژورنال
عنوان ژورنال: Journal of Experimental Botany
سال: 2006
ISSN: 0022-0957,1460-2431
DOI: 10.1093/jxb/erj211